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PEPCID® is a histamine-2 blocker (H2 blocker) with the active ingredient famotidine that helps relieve heartburn by reducing the amount of acid in the stomach.

Our Heartburn Relief Products

See Why PEPCID® Could Work For You

Pepcid vs PPI and Antacid
H2 Blocker vs. Antacid vs. PPI

Better understand the types of heartburn treatments and determine which is right for your symptoms.

Pepcid logo versus other over-the-counter heartburn relief medication
PEPCID® vs. Other OTC Heartburn Medicines

Find the best over the counter heartburn medicine which may help relieve your symptoms.

Understanding Heartburn

Woman with heartburn clutching chest
What Is Heartburn?

Heartburn is the uncomfortable burning sensation in the chest when stomach acid flows backward from your stomach to your esophagus. Learn about how it occurs here.

Pizza, oven mitt and soft drink
What Causes Heartburn?

Food and lifestyle choices can cause heartburn in anyone. Learn about common triggers that cause heartburn and what you can avoid to prevent future symptoms.

Lighter with a pepper for a flame
What Does Heartburn Feel Like?

Learn more about what heartburn feels like, common symptoms of heartburn, and how the symptoms differ from those of GERD.

Person kneeling with hands palm-up in their lap on a yoga mat
Heartburn Home Remedies & Tips

Learn how small lifestyle changes can prevent or minimize your heartburn symptoms. Check out our top tips for heartburn prevention to find what might work for you.